Dusan Misevic

Director of Research Affairs
Who I am

In his role as the Director of Research Affairs he is charting the course for CRI Research, designing and organizing the Advanced Workshops, structuring and executing the recruiting of the Research Fellows, and mentoring the Fellows. Previously he was the Scientific Coordinator for the undergraduate program Frontiers in Life Science at CRI. His background is in evolutionary and computational biology.
What I do at CRI

After graduating from Caltech in mathematics and biology, Dusan got his Ph.D from Michigan State University in evolutionary biology, working with Rich Lenski and Charles Ofria. He did a short postdoc at ETH in Switzerland with Sebastian Bonhoeffer before coming to CRI in 2009 as a postdoc in the Evolutionary and Systems Biology team of the INSERM U1001.

His most recent position at CRI was the Scientific Coordinator for the undergraduate program Frontiers in Life Science. In his present role as the Assistant Director for CRI Research he is participating in charting the course for CRI Research, designing Advanced Workshops, organising the recruiting of the Research Fellows, and mentoring the Fellows.



Research Interests

Dusan’s current main research interests concern evolution of genetic architecture and indirectly selected evolutionary traits, such as cooperation, evolvability, and mutation rate. In his research he is primarily using computational systems, including Avida, Aevol, and population genetic models, but he is also involved in microbiology projects on cooperation.

Besides research, Dusan is very interested in new education methodologies and has been teaching various courses at the undergraduate and master’s level, including Biology Bootcamp, Computer Science, Scientific Communication, Evolution, Biological Modeling, and Interdisciplinary projects. He co-designed and is involved in running a citizen science project on aging in humans, www.AgeGuess.org.

Publications

Indirect fitness benefits enable the spread of host genes promoting costly transfer of beneficial plasmids

Dimitriu, T., Misevic, D., Lotton, C., Brown, S. P., Lindner, A. B., Taddei, F. 2016. Indirect fitness benefits enable the spread of host genes promoting costly transfer of beneficial plasmids PLoS Biol 14 (6), e1002478 (pdf)

Shape matters: lifecycle of cooperative patches promotes cooperation in bulky populations

Misevic, D., Frénoy, A., Lindner, A. B., Taddei, F. 2015. Shape matters: lifecycle of cooperative patches promotes cooperation in bulky populations. Evolution, 69(3) 788-802. (pdf)

Genetic information transfer promotes cooperation in bacteria

Dimitriu, T., Lotton, C., Bénard-Capelle, J., Misevic, D., Brown, S. P., Lindner, A. B., Taddei, F. 2014. Genetic information transfer promotes cooperation in bacteria. Proceedings of the National Academy of Sciences, 11(30) 11103-11108 (pdf)

Genetic architecture promotes the evolution and maintenance of cooperation

Frénoy, A., Taddei, F. Misevic, D. 2013. Genetic architecture promotes the evolution and maintenance of cooperation. PLoS Computational Biology 9(11): e1003339. doi:10.1371/journal.pcbi.1003339 (pdf)

Sexual reproduction reshapes the genetic architecture of digital organisms

Misevic D., C. Ofria., and R. E. Lenski. 2006. Sexual reproduction reshapes the genetic architecture of digital organisms. Proceedings of the Royal Society London, Series B. 273, 457-464. (pdf)