Samir K Brahmachari

Samir K Brahmachari
CRI Research Scientific advisory board member
J.C Bose National Fellow Chief Mentor, Open Source Drug Discovery Academy Professor, Academy of Scientific & Innovative Research Scientist, Founder Director CSIR – Institute of Genomics & Integrative Biology

During his early scientific career Professor Samir K Brahmachari made fundamental contributions towards the basic understanding of structure-function relationship of peptides, proteins and DNA. Subsequently, he worked in the broader area of genome organization and function, with special focus on repetitive DNA. During the 90’s, foreseeing the potential of using the large genetic pool of Indian population for Functional Genomics studies in the post human genome sequencing era, Professor Brahmachari, established the first Functional Genomics Unit and successfully led the well-recognized Indian Genome Variation Project. This exploration of human genome variation in multi-ethnic, multilingual populations of India led to development of a national resource: the genetic profile of the people of India, later extended to all the East Asian countries.

Professor Brahmachari is the pioneer of genome analysis using computational tools. Developing developing many novel Bioinformatics tools and databases, he has made major contributions in the area of miRNA mediated regulation of host-pathogen interactions and cellular regulation. His passion towards genome analysis led him to holistically look at the Systems Biology of pathogens, and to translate the genomic knowledge thus generated, into application. The Open Source Drug Discovery platform, with its unprecedented scale of participation by students and professionals, under the innovative directions provided by Prof. Brahmachari, not only accelerates drug discovery, but also holds a promise of tremendous and disruptive impact on the economics of drug development for neglected tropical diseases like TB.

His present interest lies in the utilization of genomics and computational technology to gain a systems level understanding of pathogenic organisms and develop low cost drugs and diagnostics to achieve the vision of affordable healthcare for all.